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Alias: Tadalafei; Tadalafil
CAS No: 171596-29-5
Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Tadalafil, and under the name Adcirca for the treatment of pulmonary arterial hypertension.
Tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension.